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Vaccines with a weakened immune system will not protect millions of patients

Despite being cautious, Mr. Lotito caught the virus from his daughter in mid-October. He had a fever for about a month, and spent a week in the hospital. Antiviral plasma and Remedisvir, an anti-viral drug, relieved for a couple of weeks, but his fever returned. He finally felt better after another infusion of gamma globulin, during which he sweated through four shirts.

Even after nearly seven weeks of illness, Mr. Lotito had no antibodies to it. “I still have to take the same precautions I was taking, you know, a year ago,” he said. “It’s a bit disappointing.”

Dr. Cunningham-Rundles said that people like Mr. Lotito depend on people around them to get vaccinated to contain the virus.

“You’re hoping that your whole family members and all your close associates are going to go out and take some shots, and they’re going to provide you with protection of the herd,” she said. “That’s what you have to start.”

Dr. Cunningham-Randles has tested her patients for antibodies and has signed up a few for Regeneron’s monoclonal antibody cocktail. But many others with such conditions are not aware of their risks or their options for treatment.

The Leukemia and Lymphoma Society has established a Registry To provide information and antibody testing to people with blood cancer. And many studies are assessing reaction Vaccines in coronovirus Cancerians, Autoimmune conditions such as lupus or rheumatoid arthritis, or those taking drugs that mute the immune response.

In one such study, British researchers followed Crohn’s disease or about 7000 people with ulcerative colitis from 90 hospitals in the country. They found that Less than half the patients The remicade that took place triggered an immune response after a coronovirus infection.